Evernorth EnGuide Pharmacy is dedicated solely to dispensing, packaging, and shipping GLP-1 medications. Given the complexity of these medications, Evernorth EnGuide Pharmacy benefits from a staff of pharmacists specially trained in GLP-1s, giving a more focused level of care to patients and helping them get on the right dose long-term, while advising on any potential side effects.

For home delivery, you may previously have received your GLP-1 medications from Express Scripts^® Pharmacy, our home delivery pharmacy, but as of June 15, 2025, you’ll be receiving your GLP-1 medications through Evernorth EnGuide Pharmacy. You may also choose to fill at other in-network pharmacies.

GLP (glucagon-like peptide-1) medications are a class of drugs used primarily to treat type 2 diabetes and obesity. They work by mimicking a natural hormone called GLP-1, which helps regulate blood sugar levels, appetite, and digestion. Common brand names for GLP-1s include Ozempic^®, Wegovy^®, Mounjaro^®, and Zepbound^®.

Evernorth EnGuide Pharmacy is available to you if you have pharmacy benefits from Express Scripts and other participating pharmacy benefit managers.

Additionally, your plan sponsor must have selected Evernorth EnGuide Pharmacy to be in your network. You can check to see if you have Evernorth EnGuide Pharmacy in your network by logging in to, or registering, your Express Scripts account.

If Evernorth EnGuide Pharmacy is available to you, you’ll be able to order or refill your GLP-1s from your medication dashboard. If you have a new GLP-1 prescription, you’ll need to have your prescription sent to Evernorth EnGuide Pharmacy. The fastest way to get your medications is to have your prescriber electronically send your prescription.

You can also go to the “Request an Rx” button on the Dashboard and place your order there.

Please note that a subset of patients taking a GLP-1 for weight loss will need to be enrolled and engaged in a lifestyle modification program before receiving the medication. This requirement is chosen by your employer or health plan. You will be notified if you are in this program and advised what to do when you place your medication order.

With Evernorth EnGuide Pharmacy, you can enjoy the convenience of getting your GLP-1 medications shipped directly to your home or office. In addition, Evernorth EnGuide Pharmacy offers:

• Simple, stress-free ordering
• Free standard shipping (note: standard shipping costs are included as part of your prescription plan)
• Flexible payment options with no fees (note: not available for Medicare or Medicaid)
• Assistance with manufacturer coupons to reduce costs
• 24/7 support, including access to pharmacists trained in GLP-1 conditions
• Support getting safely on the correct long-term dose for you
• Access to a comprehensive library, including videos, so you can learn more about your GLP-1 and the conditions it treats

You will need to have your prescription sent to Evernorth EnGuide Pharmacy to get started. The fastest way to get your medication is to have your prescriber electronically send it.

Find out more about getting started

No pharmacy can guarantee supply. Evernorth EnGuide Pharmacy provides consistent access to fills, if supply is available, for both 30- and 90-day amounts. Access to fills is important since many pharmacies are starting to limit fills and/or not dispensing at all, and this is expected to become more common.

A 30-day supply helps you to find the optimal dose that works for you. Your prescriber will generally start on a lower-strength level and then increase that strength level monthly until it works well for you. Additionally, some patients may have adverse side effects that require them to switch brands: having a 30-day supply is best for those situations.

However, once you are stable on a long-term dose, it’s advantageous to request a 90-day supply. Having a 90-day supply allows you to have more immediately available, which can be helpful in the case of ongoing shortages. With the extended payment plan, you can split the amount you pay into three equal payments.

Find out how to use the extended payment plan

It’s very safe. Millions of people have their medications delivered every day. We make sure packaging is confidential, tamper evident, and weather resistant. Since your medication requires specific temperature control, Evernorth EnGuide Pharmacy has proprietary packaging and coolant packs, adjusting for weather forecast and climate.

Once we receive your prescription from your prescriber, our pharmacists perform a clinical safety check against other medications you may be taking. From there, your medication is packaged at our dedicated pharmacy, and shipped using proprietary packaging and coolant packs, adjusting for weather forecast and climate.

A new prescription will take approximately 3-5 days to reach your home after the prescription is received, with refills delivered approximately 3-5 days after being ordered. You’ll receive communications on the status of your medication every step of the process, from receipt of prescription to processing to shipping to delivery to your home.

Tips to get your prescription faster:

• Have your prescriber electronically send your prescription to Evernorth EnGuide Pharmacy.
• Order your refill as soon as you can place an order.
• Choose the method of refill reminder that you’ll be most likely to quickly respond to: notification, text, or email.
• When you get your refill reminder communication, order immediately.
• Expedited shipping is always available, although there will be a fee.

If you have questions about your shipment, please call the customer service number on the back of your digital ID card.

You’ll also get real-time updates as we fill and ship your order in your online account, as well as texts and/or email notifications.

Our pharmacists are readily available to address your needs and are able to spend the time you need to get your questions thoroughly answered. Even better, all conversations take place from the privacy of your home or from wherever you choose. Simply log in to your Express Scripts account for help with your prescription or prescription benefit.

At this time, manufacturer's coupons will be accepted. You will need access to information on your Savings Card for our team to process the coupon. Whether or not the card is applied depends on the terms and conditions set by the card's sponsor – typically the drug manufacturer. If the card is not able to be applied to your prescription order, your prescription will continue to process as usual, and you will be responsible for your standard copay or coinsurance amount.